Correlation of Obstructed Defecation Syndrome with Pelvic Organ Prolapse and Anorectal Manometry

Background and Objective: Defecatory dysfunction is a common problem among women who are referred for urogynecological care. Pelvic organs prolapse (POP) which is a downward displacement of pelvic organs is one of the common conditions among patients with defecatory problems. This study was planned to evaluate the correlation of obstructive defecatory symptoms with the site and severity of pelvic organ prolapse and the anorectal manometry results. Methods: This cross-sectional study was performed between Dec ۲۰۱۸ and Nov ۲۰۱۹. A total of ۱۵۰ women with symptoms of defecatory problems were enrolled. Patients were classified in two groups according to each compartment prolapse staging and severity: stage ≤۲ and stage >۲. The correlation between defecatory symptoms and pelvic organ prolapse examination, anorectal examination and anal manometry were evaluated. Results: A total of ۱۵۰ women were evaluated. There was a significant correlation between higher stage of anterior compartment prolapse (cystocele stage>۲) and constipation (P=۰.۰۳۵). Although all the defecatory symptoms were more frequent in anterior prolapse stage>۲, but the difference was not significant (P>۰.۰۵). There was no significant correlation between defecatory symptoms and severity of posterior compartment prolapse. There was a significant correlation between stage>۲ of apical prolapse and all the defecatory symptoms (P≤۰.۰۵). The abnormal anal resting and squeeze pressure and abnormal balloon expulsion test were more frequent in stage >۲ of all compartments prolapse, but the difference was not significant (P>۰.۰۵). Conclusion: Obstructed defecation syndrome was more frequent in patients with higher stages of anterior and apical prolapse. Abnormal manometry results were more frequent in patients with defecatory dysfunction with advanced vaginal prolapse.