Advances in early detection and therapies have prompted an increased number of cancer survivors throughout the most recent twenty years. Concerning this population, it is essential to assess the long-term impacts of cancer treatment and create recommendations about caring for these survivors. There is increasing proof linking so-called energy balance factors (body weight, diet, and physical activity) tothe risk of developing cancer and likely cancer-related outcomes and gives clinical suggestions for cancer survivors. Weight Management; Various molecular have been advanced to clarify the relationship between body weight and cancer risk, including altered levels of hormones and growth factors, insulin resistance, and PI3K-AKT-mTOR signaling pathway alterations. Weight gain or loss should be managed with a mix of dietary, physical activity, and behavioral strategies. Limiting portion sizes, particularly of energy-dense foods, is an important weight reduction strategy. Dietary Supplements: with expanding information about the significance of more advantageous habits to prevent cancer, survivors are motivated to improve their lifestyle propensities after diagnosis, including improvements in diet. A diet rich in vegetables, fruits, and whole grains, with less accentuation on animal proteins, is recommended. Prescribed sources of dietary fat include plant sources and fatty fish, as opposed to red meats. Physical Activity: Routine physical activity may create modifications in immune function, oxidative harm, and the insulin axis that may affect cancer metabolism. Exercise training exerts anti-inflammatory and anti-proliferative impacts by diminishing levels of elements like cyclooxygenase-2 (COX-2), inducible nitric oxide synthase, and TNF-α, all of which play a role in tumorgenesis. Physical activity may improve treatment-related side effects, likewise helpful in addressing chronic fatigue during and after cancer therapy. Expanding proof is highlighting the role of lifestyle behaviors in influencing cancer-related outcomes. Obesity, poor diet and inactivity have more than once been appeared to contrarily affect outcomes in patients. In spite of the currently available data suggest a strong relationship between lifestyle factors and cancer outcomes, randomized trials are expected to test the effect of deliberate weight reduction, dietary alteration, and increased physical activity on the danger of related results in cancer survivors. What s more, assessment of the biologic mechanisms underlying how lifestyle changes and health behaviors influence cancer outcomes is required.