Experimental study of the physical property of nano crystalline hydroxyapatite for orthopedic and dental applications

Hydroxyapatite (HA) is a well-known key bioceramic material frequently used as a ocular implant, bone substitute for filling bone defects, scaffold matrix for tissue engineering and as a coating agent on biomedical implants due to its chemical and biological similarity with natural bone mineral. It is known to be biocompatible, bioactive i.e. ability to form a direct chemical bond with living tissues, biodegradable and osteoinductive. Resorbability of HA can be improved with help of reducing its grain size to nano-level. In these study we evaluate some physical property of ncHA that prepared by wet chemical reaction. We have used X-ray diffraction analysis (XRD) to determine the phase compositions and the crystalline states. The crystallite morphology of the samples was analyzed in a (TEM) and Fourier Transform Infrared (FTIR) spectroscopy to identify the functional groups The results indicated that it has nano scale morphological structure with mean particle size of 60-70 nm and also has chemical composition similar to natural bone apatite.