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مقالات فارسیISIکنفرانسهاژورنالها

A review on electrospun nanofibers for oral drug delivery

محل انتشار: مجله علوم نانو، دوره: 4، شماره: 4
سال انتشار: 1396
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 405

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لینک ثابت به این مقاله:
https://civilica.com/doc/893422

شناسه ملی سند علمی:

JR_NAMJ-4-4_001

تاریخ نمایه سازی: 18 تیر 1398

چکیده مقاله:

Nowadays, polymer nanofibers have gained attention due to remarkable characteristics such as high porosity and large surface area to volume ratio. Among their fabrication methods, electrospinning technique has been attracted as a simple and reproducible approach. It is a versatile, simple and cost-effective technique for the production of continuous nanofibers with acceptable characteristics such as high porosity, high surface area to volume ratio, high loading capacity and encapsulation efficiency, delivery of multiple drugs, and enhancement of drug solubility. Due to these properties electrospun nanofibers have been extensively used for different biomedical applications including wound dressing, tissue engineering, enzyme immobilization, artificial organs, and drug delivery. Different synthetic and natural polymers have been successfully electrospun into ultrafine fibers. Using electrospun nanofibers as vehicles for oral drug delivery has been investigated in different release manners- fast, biphasic or sustained release. This article presents a review on application of electrospinning technique in oral drug delivery.    

کلیدواژه ها:

Nanofiber ، Electrospinning ، Drug Delivery ، Polymer

نویسندگان

Abbas Akhgari

Targeted Drug Delivery Research Center, Mashhad University of Medical Sciences, Mashhad, Iran|School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran

Zahra Shakib

School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran

Setareh Sanati

School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran

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