Protective effect of royal jelly on the sperm parameters and testosterone level and lipid peroxidation in adult mice treated with oxymetholone

سال انتشار: 1393
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 331

فایل این مقاله در 10 صفحه با فرمت PDF قابل دریافت می باشد

این مقاله در بخشهای موضوعی زیر دسته بندی شده است:

استخراج به نرم افزارهای پژوهشی:

لینک ثابت به این مقاله:

شناسه ملی سند علمی:

JR_AJP-4-1_005

تاریخ نمایه سازی: 1 مهر 1398

چکیده مقاله:

Objectives: The aim of the present study was to evaluate protective effect of royal jelly on sperm parameters, testosterone level, and malondialdehyde (MDA) production in mice. Materials and Methods: Thirty-two adult male NMRI mice weighing 30±2 g were used. All the animals were divided into 4 groups. Control group: received saline 0.1 ml/mouse/day orally for 30 days. Royal Jelly group (RJ): received royal jelly at dose of 100 mg/kg daily for 30 days orally. Oxymetholone group: the received Oxymetholone (OX) at dose of 5 mg/kg daily for 30 days orally. Royal Jelly+Oxymetholone group: received royal jelly at dose of 100 mg/kg/day orally concomitant with OX administration. Sperm count, sperm motility, viability, maturity, and DNA integrity were analyzed. Furthermore, serum testosterone and MDA concentrations were determined. Results: In Oxymetholone group, sperm count, motility as well as testosterone concentration reduced significantly (p<0.05), while significant (p<0.05) increases in immature sperm, sperm with DNA damaged, and MDA concentration were announced in Oxymetholone group in comparison with control group and Royal Jelly+Oxymetholone group. RJ caused partially amelioration in all of the above- mentioned parameters in Royal Jelly+Oxymetholone group. Conclusion: In conclusion, RJ may be used in combination with OX to improve OX-induced oxidative stress and male infertility.

کلیدواژه ها:

نویسندگان

Ensieh Zahmatkesh

Department of Histology and Embryology, Faculty of Science, Urmia University, Urmia, I. R. Iran

Gholamreza Najafi

Department of Anatomy and Embryology, Faculty of Veterinary Medicine, Urmia University, Urmia, I. R. Iran

Vahid Nejati

Department of Histology and Embryology, Faculty of Science, Urmia University, Urmia, I. R. Iran

Reza Heidari

Department of Biochemistry, Faculty of Science, Urmia University, Urmia, I. R. Iran

مراجع و منابع این مقاله:

لیست زیر مراجع و منابع استفاده شده در این مقاله را نمایش می دهد. این مراجع به صورت کاملا ماشینی و بر اساس هوش مصنوعی استخراج شده اند و لذا ممکن است دارای اشکالاتی باشند که به مرور زمان دقت استخراج این محتوا افزایش می یابد. مراجعی که مقالات مربوط به آنها در سیویلیکا نمایه شده و پیدا شده اند، به خود مقاله لینک شده اند :
  • Ahmed T, Abdelhafiza B, Jehan A. 2008. Muhamad b Midcyclepericoitalintravaginal ...
  • Aitken RJ. 1994. A free radical theory of male infertility. ...
  • Aitken RJ. 1995. Free radicals, lipid peroxidation and sperm function. ...
  • Birkhead TR, Martinez, JG, Burke T, Froman, DP. 1999. Sperm ...
  • Bjorndahl L, Soderlund I, Kvist U. 2003.Consider replacing with Evaluation ...
  • Bungum M, Bungum L, Giwercman A. 2011.Sperm chromatin structure assay ...
  • Carrell DT, Emery, BR, Hammoud S. 2007. Altered protamine expression ...
  • Chang H, Suarez SS. 2011. Two distinct Ca2+ signaling pathways ...
  • Christiansen K. 2001. Behavioural Effects of Androgen in Men and ...
  • Collar ML, Hines M. 1995. Human behavioral sex differences: A ...
  • Comhaire FH, Christophe AS, Zalata AA, Dhooge WS, Mahmoud AM, ...
  • Dziuk PJ. 1996. Factors that influence the proportion of offspring ...
  • Esposito G, Jaiswal BS, Xie F, Krajnc-Franken, MA, Robben TJ, ...
  • Fraser L, Strzezek J. 2007. Effect of different procedures of ...
  • Fujii A, Kobayashi S, Kuboyama N. 1990. Augmentation of wound ...
  • Glander HJ, Kratzsch J,Weisbrich C, Birkenmeier G. 1996 .Insulin-like growth ...
  • Gomez E, Irvine DS, Aitken RJ. 1998. Evaluation of a ...
  • Hafez B, Hafez ESE. 2000. Reproduction in Farm Animals, pp. ...
  • Hashimoto M, Kanda M, Ikeno K, Hayashi Y, Nakamura T. ...
  • Hattori N, Nomoto H, Fukumitsu H, Mishima S, Furukawa Sh. ...
  • Haupt HA, Rovere GD. 1984.Anabolic steroids. A review of the ...
  • Hayes K J. 1965. The so called levatorani of the ...
  • Henricks  D.M, Kouba AJ, Lackey BR, Boone WR, Gray SL. ...
  • Hosseinzadeh H, sadeghnia RH. 2005. Safranal, aconstituent of corcussativus, attenuated ...
  • Hunter FM, Birkhead TR. 2002.Sperm viability and sperm competition in ...
  • Juris E, Janis B, Vika L, Jekaterina E, Janis Z. ...
  • Kanbur M, Eraslan G, Silici S, Karabacak M. 2009. Effects ...
  • Kendall D. 1948. Thrombosis of intracranial veins. Brain, 71: 386-402. ...
  • Kincl FA, Macqueo M, Dorfman R. 1965. Influence of various ...
  • Klaiber  EL, Henzl  MR, Lloyd  CW, Segre  EJ. 1973. Corpus ...
  • Lejeune  H , Chuzel  F , Thomas  T, Avallet O, ...
  • Lishko PV, Botchkina IL, Kirichok Y. 2011. Progesterone activates the ...
  • Morris ID, Ilott S, Dixon L, Brison DR. 2002. The ...
  • Nagai T, Inoue R. 2004. Preparation and the functional properties ...
  • Nakajima Y, Tsuruma K, Shimazawa M, Mishima S, Hara H. ...
  • Nolan MA, Babcock  DF, Wennemuth  G, Brown W, Burton  KA, ...
  • Orlande F, Jezequel A, Melliti A. 1964. The action of ...
  • Overly WL, Dankoff JA, Wong BK, Sengh UD. 1984. Androgens ...
  • Quill TA, Sugden SA, Rossi KL, Doolittle LK, Hammer RE, ...
  • Renard P, Grizard G, Griveau JF, Sion B, Boucher D, ...
  • SanchezPena LC, Reyes BE,LopezCarrillo L,Recio R,MoranMartinez J, Cebrian ME,QuintanillaVega B. ...
  • Sandifer SH, Wilkins R, Loadholt CB, Lane LG, ldridge JC. ...
  • Sanocka  D, Kurpisz  M. 2004. Reactive oxygen species and sperm ...
  • Shimoda M, Nakajin S, Oikawa T. 1978. Biochemical studies on ...
  • Sver L, Orsolic N, Tadic Z. 1996. A royal jelly ...
  • Takenaka T. 1982. Chemical composition of royal jelly. Honeybee Sci, ...
  • Talebi AR, Moein MR, Tabibnejad N, Ghasemzadeh J. 2008. Effect ...
  • Vannelli  BG, Barni  T, Orlando C, Natali A, Serio  M, ...
  • Vickers MH, Casey PJ, Champion ZJ, Gravance CG, Breier BH. ...
  • Whorton D, Krauss R, Marshall S, Milby T. 1977. Infertility ...
  • World Health Organization. laboratory manual for the examination of human ...
  • Wyrobek AJ, Bruce WR. 1975. Chemicalinduction of sperm abnormalities in ...
  • Yang A, Zhou M, Zhang L, Xie G, Chen H, ...
  • Zeng XH, Yang C, Kim ST, Lingle CJ, Xia XM. ...
  • نمایش کامل مراجع