Effects of fasting on peripapillary capillary density, peripapillary nerve fiber layer, intraocularpressure and central corneal thickness
محل انتشار: بیست و نهمین کنگره سالیانه انجمن چشم پزشکی ایران
سال انتشار: 1398
نوع سند: مقاله کنفرانسی
زبان: انگلیسی
مشاهده: 565
نسخه کامل این مقاله ارائه نشده است و در دسترس نمی باشد
- صدور گواهی نمایه سازی
- من نویسنده این مقاله هستم
استخراج به نرم افزارهای پژوهشی:
شناسه ملی سند علمی:
ACSOMED29_001
تاریخ نمایه سازی: 30 آذر 1398
چکیده مقاله:
Purpose: To investigate the effects of fasting on intraocular pressure (IOP), central corneal thickness (CCT),radial peripapillary capillary (RPC) density and retinal nerve fiber layer (RNFL) thickness during Islamic fastingmonth of Ramadan.Methods: 27 healthy fasting volunteers were enrolled. All subjects underwent full ophthalmic examination andoptical coherence tomography angiography (OCTA) of both eyes. All measurements were recorded first in themorning (8:00-10:00 am) and then in the evening (4:00-6:00 p.m.). First visit was performed during the 2nd and3rd week of Ramadan and then two months later in a nonfasting routine day.Results: Mean age of participants was 40.07±9.29 years. A significant decrease was found for evening IOP(11.17±2.29 mmHg) in comparison to morning IOP (12.00±2.28) (p=0.00) only on fasting days. A decrease wasobserved for CCT both on fasting (6 μm) and nonfasting days (3 μm) (p=0.00 and p=0.02 respectively) in theevening. There was a significant increase in whole and peripapillary RPC density (%) on fasting days (48.79±3.08morning, 49.72±2.85 evening for whole and 50.57±4.06 morning, 51.64±3.71 evening for peripapillary) (p=0.00).Average RNFL thickness was decreased from morning to evening both on fasting days (0.80 μm) and nonfastingdays (1.25 μm) (p=0.00). Optic nerve head (ONH) vertical cup/disc (C/D) ratio was greater on fasting days(0.30±0.25 morning, 0.31±0.24 evening) in comparison to nonfasting days (0.27±0.25 morning, 0.28±0.25evening) (p=0.02).Conclusion: Fasting decreases the IOP and CCT in healthy subjects. OCTA revealed significant difference inRPC vessel density, RNFL thickness and ONH vertical C/D ratio during fasting hours in comparison to nonfastingdays.
نویسندگان
Naveed Nilforushan
Eye Research Center, Rassoul Akram Hospital, Iran University of Medical Sciences, Tehran, Iran
Navid Abolfathzadeh
Eye Research Center, Rassoul Akram Hospital, Iran University of Medical Sciences, Tehran, Iran
Mohammad Banifatemi
Eye Research Center, Rassoul Akram Hospital, Iran University of Medical Sciences, Tehran, Iran
Arezoo Miraftabi
Eye Research Center, Rassoul Akram Hospital, Iran University of Medical Sciences, Tehran, Iran
Mahsa Sardarinia
Eye Research Center, Rassoul Akram Hospital, Iran University of Medical Sciences, Tehran, Iran
Sayyed Amirpooya Alemzadeh
Eye Research Center, Rassoul Akram Hospital, Iran University of Medical Sciences, Tehran, Iran