Serum lactate is a useful predictor of death in severe sepsis and septic shock
محل انتشار: مجله پزشکی بالینی، دوره: 1، شماره: 3
سال انتشار: 1393
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 292
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شناسه ملی سند علمی:
JR_RCM-1-3_002
تاریخ نمایه سازی: 2 دی 1398
چکیده مقاله:
The severe sepsis and septic shock are as common and lethal that emergency physicians routinely confront. Actually, more than two thirds of sepsis patients present initially to the ED. Only a few laboratory tests for markers of sepsis are currently available. The serum lactate level can help in determining prognosis and to risk-stratify patients with severe sepsis. This independent review of the literature includes 83 studies published in all electronic-based database such as Elsevier, PubMed, and SID during the last 18 years (40–320 patients in each). Data gathered from English language articles and books published between 1995 and 2013. The serum lactate concentrations measured in almost all patients with severe sepsis raised at admission and were higher in patients who had the worst outcomes such as higher Apache-II and SOFA score. Serum lactate was associated with mortality independent of clinically apparent organ dysfunction and shock in patients with severe sepsis admitted to the emergency department and intensive care unit. This review focuses on the association between initial and serial serum lactate level and mortality in patients presenting to the emergency department with severe sepsis.
کلیدواژه ها:
نویسندگان
Jafar Malmir
Department of Emergency Medicine, Imam Reza hospital, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
Ehsan Bolvardi
Department of Emergency Medicine, Imam Reza hospital, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
Monavar Afzal Aghaee
Department of Community medicine, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
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