The effect of Tranexamic acid on cardiac surgery bleeding

سال انتشار: 1393
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 332

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شناسه ملی سند علمی:

JR_RCM-1-1_002

تاریخ نمایه سازی: 2 دی 1398

چکیده مقاله:

Serious bleeding in cardiac surgery leads to re-exploration, blood transfusion and increases the risks of mortality and morbidity. Using the lysine analogous of antifibrionlytic agents are the preferred strategy to suppress the need for transfusion procedures and blood products. Although tranexamic acid has been very influential in reducing the transfusion requirement after operation, tranexamic acid induced seizures is one of the common side effects of this drug. Due to inhibiting the fibrinolysis, thrombotic events are other possible side effects of using tranexamic acid. There are no certain results regarding decreasing the mortality rate by using the drug but it is identified that tranexamic acid does not increase the mortality. In this article, we aimed to review the literature on using tranexamic acid in cardiac surgeries.

نویسندگان

Mohammad Esmaeelzadeh

Department of Anesthesiology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

Shahram Amini

Department of Anesthesiology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

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  • Daly DJ, Myles PS, Smith JA, et al. Anticoagulation, bleeding ...
  • Rogers MA, Blumberg N, Saint SK, et al. Allogeneic blood ...
  • Murphy GJ, Reeves BC, Rogers CA, et al. Increased mortality, ...
  • Hamaguchi I. Blood transfusion and infectious diseases. Rinsho Byori. 2013;61:414-417. ...
  • McQuilten ZK, Andrianopoulos N, Wood EM, et al. Transfusion practice ...
  • Tzortzopoulou A, Cepeda MS, Schumann R, et al. Antifibrinolytic agents ...
  • Zufferey P, Merquiol F, Laporte S, et al. Do antifibrinolytics ...
  • Lethaby A, Farquhar C, Cooke I. Antifibrinolytics for heavy menstrual ...
  • Chuong CJ, Brenner PF. Management of abnormal uterine bleeding. Am ...
  • Schmarts. Antifibrinolytics. Acta Anaesthesiol Belg. 2003;54:319-322. ...
  • Dowd NP, Karski J, Cheng D, et al. Pharmacokinetics of ...
  • Dunn CJ, Goa KL. Tranexamic acid: a review of its ...
  • Dhir A. Antifibrinolytics in cardiac surgery. Ann Card Anaesth. 2013;16:117-125. ...
  • Ker K, Edwards P, Perel P, et al. Effect of ...
  • Henry D, Carless P, Moxey A, et al. Anti-fibrinolytic use ...
  • Guenther CR. Pro: tranexamic acid is better than aprotinin in ...
  • Bell D, Marasco S, Almeida A, et al. Tranexamic Acid ...
  • Murkin JM, Falter F, Granton J, et al. High-dose tranexamic ...
  • Montes FR, Pardo Df, Carreno M, et al. Risk factors ...
  • Manji RA, Grocott HP, Leake J, et al. Seizures following ...
  • Martin K, Wiesner G, Breuer T, et al. The risks ...
  • Lecker I, Wang DS, Romaschin AD, et al. Tranexamic acid ...
  • Shakur H, Roberts I, Bautista R, et al. Effects of ...
  • Verstraete M. Clinical application of inhibitors of fibrinolysis. Drugs. 1985;29:236-261. ...
  • Koster A, Borgermann J, Zittermann A, et al. Moderate dosage ...
  • Armellin G, Vinciguerra A, Bonato R, et al. Tranexamic acid ...
  • Fiechtner BK, Nuttall GA, Johnson ME, et al. Plasma tranexamic ...
  • نمایش کامل مراجع