Four-Component Synthesis of Polyhydroquinolines via Unsymmetrical Hantzsch Reaction Employing Cu-IRMOF-۳ as a Robust Heterogeneous Catalyst

In this report, an IRMOF-۳ was synthesized via a solvothermal method and then used as support for stabilizing Cu(II) ions. Characterization methods such as FT-IR, XRD, SEM, and BET were employed to analyze produced Cu@IRMOF-۳, demonstrating that the suggested catalyst effectively conserved its structure throughout the synthesis processes. The FT-IR results indicate that the presence of the -NH۲ group in the structure of the MOF helped stabilize the Cu(II) ions. The manufactured catalyst was used to prepare polyhydroquinoline derivatives which showed superior results.