ورود
مقالات فارسیISIکنفرانسهاژورنالها

The Relationship Between Serum Uric Acid and Cardiometabolic Risk Factors in Iranian Children and Adolescents

محل انتشار: مجله پزشکی کودکان، دوره: 9، شماره: 2
سال انتشار: 1400
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 49

فایل این مقاله در 8 صفحه با فرمت PDF قابل دریافت می باشد

استخراج به نرم افزارهای پژوهشی:

لینک ثابت به این مقاله:
https://civilica.com/doc/1837754

شناسه ملی سند علمی:

JR_JPRE-9-2_011

تاریخ نمایه سازی: 9 آذر 1402

چکیده مقاله:

Context: There has been an increasing interest in epidemiological and clinical studies concerning the role of uric acid in cardiometabolic diseases, especially in children and adolescents. However, these potential relationships remain undiscovered; accordingly, its pathophysiological mechanisms remain unrecognized. This study aimed to assess the potential association between Serum Uric Acid (SUA) levels and cardiometabolic risk factors in a population-based sample of Iranian children and adolescents.  Objectives: This study aimed to assess the potential association between Serum Uric Acid (SUA) levels and cardiometabolic risk factors in a population-based sample of Iranian children and adolescents. Methods: The data of ۵۹۵ individuals aged ۷-۱۸ years were assessed in this research. Anthropometric measurements and laboratory tests were performed according to standardized protocols. Results: The Mean±SD age of the ۵۹۵ explored students was ۱۲.۳۹±۳.۰۷ years. The overall Mean±SD SUA level of the study participants was measured as ۴.۲۲±۱.۱۳ mg/dL, with significant gender-wise differences (۴.۰۴±۰.۹۷ mg/dL vs ۴.۳۸±۱.۲۴ mg/dL, respectively; P<۰.۰۵). The prevalence of hyperuricemia based on the ۹۰th percentile of SUA levels was equal to ۱۰.۶%. There was a positive association between SUA levels and abdominal obesity (waist circumference: ≥۹۰th percentile) [Odds Ratio (OR): ۱.۵۴; ۹۵% Confidence Interval (CI): ۱.۲۶ to ۱.۸۶] and general obesity [gender-specific Body Mass Index (BMI) for >۹۵th percentile] (OR: ۲.۳۲; ۹۵% CI: ۱.۷۴ to ۳.۱۱). Conclusions: This study suggested BMI and waist circumference as cardiometabolic risk factors, i.e. significantly associated with SUA levels in children and adolescents.

کلیدواژه ها:

Uric acid ، Metabolic syndrome ، Obesity ، Risk factors

نویسندگان

Motahar Heidari-Beni

Department of Nutrition, Child Growth and Development Research Center, Research Institute for Primordial Prevention of Non-communicable Disease, Isfahan University of Medical Sciences, Isfahan, Iran.

Roya Riahi

Department of Pediatrics, Child Growth and Development Research Center, Research Institute for Primordial Prevention of Non-communicable Disease, Isfahan University of Medical Sciences, Isfahan, Iran.

Fatemeh Mohebpour

Department of Pediatrics, Child Growth and Development Research Center, Research Institute for Primordial Prevention of Non-communicable Disease, Isfahan University of Medical Sciences, Isfahan, Iran.

Majid Khademian

Department of Pediatrics, Child Growth and Development Research Center, Research Institute for Primordial Prevention of Non-communicable Disease, Isfahan University of Medical Sciences, Isfahan, Iran.

Roya Kelishadi

Department of Pediatrics, Child Growth and Development Research Center, Research Institute for Primordial Prevention of Non-communicable Disease, Isfahan University of Medical Sciences, Isfahan, Iran.

مراجع و منابع این مقاله:

لیست زیر مراجع و منابع استفاده شده در این مقاله را نمایش می دهد. این مراجع به صورت کاملا ماشینی و بر اساس هوش مصنوعی استخراج شده اند و لذا ممکن است دارای اشکالاتی باشند که به مرور زمان دقت استخراج این محتوا افزایش می یابد. مراجعی که مقالات مربوط به آنها در سیویلیکا نمایه شده و پیدا شده اند، به خود مقاله لینک شده اند :
  • Luciano R, Shashaj B, Spreghini M, Del Fattore A, Rustico ...
  • Özalp Kızılay D, Şen S, Ersoy B. Associations Between Serum ...
  • Fu S, Luo L, Ye P, Xiao W. Epidemiological associations ...
  • Khan A, Shah MH, Khan S, Shamim U, Arshad S. ...
  • Bassols J, Martínez-Calcerrada JM, Prats-Puig A, Carreras-Badosa G, Díaz-Roldán F, ...
  • Scheepers LE, Boonen A, Pijnenburg W, Bierau J, Staessen JA, ...
  • Sharaf El Din UAA, Salem MM, Abdulazim DO. Uric acid ...
  • Borghi C, Palazzuoli A, Landolfo M, Cosentino E. Hyperuricemia: a ...
  • Xiong Q, Liu J, Xu Y. Effects of Uric Acid ...
  • Motlagh ME, Ziaodini H, Qorbani M, Taheri M, Aminaei T, ...
  • WHO Child Growth Standards based on length/height, weight and age. ...
  • Moulin-Mares SRA, Oliosa PR, Faria ER, Zago-Gomes MP, Mill JG. ...
  • Cook S, Weitzman M, Auinger P, Nguyen M, Dietz WH. ...
  • Petrikova J, Janicko M, Fedacko J, Drazilova S, Madarasova Geckova ...
  • Ndrepepa G. Uric acid and cardiovascular disease. Clinica chimica acta; ...
  • Lee SJ, Oh BK, Sung KC. Uric acid and cardiometabolic ...
  • Cortese F, Scicchitano P, Meliota G, Giordano P, Ciccone MM. ...
  • Sun D, Li S, Zhang X, Fernandez C, Chen W, ...
  • Chen Q, Yin YJ, Chen WY, Wu JN, Huang X. ...
  • Ford ES, Li C, Cook S, Choi HK. Serum concentrations ...
  • Li N, Zhang S, Li W, Wang L, Liu H, ...
  • Cardoso AS, Gonzaga NC, Medeiros CC, Carvalho DF. Association of ...
  • King C, Lanaspa MA, Jensen T, Tolan DR, Sánchez-Lozada LG, ...
  • Grayson PC, Kim SY, LaValley M, Choi HK. Hyperuricemia and ...
  • Ishizaka N, Ishizaka Y, Toda A, Tani M, Koike K, ...
  • Lurbe E, Torro MI, Alvarez-Pitti J, Redon J, Borghi C, ...
  • Song C, Zhao X. Uric acid promotes oxidative stress and ...
  • Kubota M. Hyperuricemia in Children and Adolescents: Present Knowledge and ...
  • Wang Y, Hu JW, Lv YB, Chu C, Wang KK, ...
  • Bjornstad P, Snell-Bergeon JK, McFann K, Wadwa RP, Rewers M, ...
  • Cicero AF, Rosticci M, Bove M, Fogacci F, Giovannini M, ...
  • Pearson TA, Blair SN, Daniels SR, Eckel RH, Fair JM, ...
  • Feig DI, Kang DH, Johnson RJ. Uric acid and cardiovascular ...
  • Song K, Wang Y, Wang G, Zhang Q, Jiao H, ...
    • نمایش کامل مراجع