Effects of Rosmarinus officinalis and Platanus orientalis extracts on asthmatic subjects resistant to routine treatments

سال انتشار: 1397
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 293

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شناسه ملی سند علمی:

JR_AJP-8-5_002

تاریخ نمایه سازی: 18 تیر 1398

چکیده مقاله:

Objective: The present study aimed to determine the effects of Rosmarinus officinalis (R. officinalis) and Platanus orientalis(P. orientalis) extracts on asthma. Materials and Methods: We conducted a randomized, double-blind, active-comparator study to evaluate the effect of P. orientalis and R. officinalis extracts on asthmatic patients resistant to routine treatment.The subjects were randomly divided into three groups receiving P. orientalis and R. officinalis extracts alone or in combination. The primary endpoints were clinical findings, spirometry, exhaled nitric oxide (FENO) and Asthma Control Test (ACT) assessed over the one-month treatment period. Results: ACT score showed significant improvement after treatment with R. officinalis (p<0.05) but not with P. orientalis. Clinical evaluations showed that cough, sputum production and wheezing were significantly improved in R. officinalis group (p Conclusion: R. officinalis extract showed promising results in treatment of resistant asthma. Further studies to find the most effective components of these herbal medicines are recommended.

نویسندگان

Majid Mirsadraee

Department of Internal medicine, Faculty of Medicine, Islamic Azad University-Mashhad Branch, Mashhad, Iran

Afsaneh Tavakoli

Innovative Medical Research Center, Department of pharmacology, Mashhad Branch, Islamic Azad University, Mashhad, Iran

Vahideh Ghorani

Neurogenic Inflammation Research Centre and Department of Physiology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

Shadi Ghafari

Biologist, Shahid Hasehemi Nezhad Research center, Kavosh high school, Ministry of Education, Mashhad, Iran

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  • Aggarwal BB, Shishodia S. 2004. Suppression of the nuclear factor-kappaB ...
  • Al-Sereiti MR, Abu-Amer KM, Sen P. 1999. Pharmacology of rosemary ...
  • Aqel MB. 1991. Relaxant effect of the volatile oil of ...
  • Bai N, He K, Roller M, Lai C, Shao X, ...
  • Chirumbolo S. 2010. The role of quercetin, flavonols and flavones ...
  • Eftekhar N, Moghimi A, Boskabady MH. 2017. Prophylactic effect of ...
  • Emami F, Ali-Beig H, Farahbakhsh S, Mojabi N, Rastegar-Moghadam B, ...
  • Encyclopedia Iranica. Vol. V, Fasc. 2, pp. 129-133. Available at: ...
  • Global initiative for asthma, Pocket guide for asthma management and ...
  • Hajhashemi V, Ghannadi A, Mousavi S. 2011. Antinociceptive study of ...
  • Inoue K, Takano H, Shiga A, Fujita Y, Makino H, ...
  • Irtiza S, Bhat GA, Ahmad M, Ganaie HA, Ganai BA, ...
  • Mehni F, Sharififar F, Ansari M. 2012. Antioxidant activity and ...
  • Miller MR, Hankinson J, Brusasco V, Burgos F, Casaburi R, ...
  • Mitrokotsa D, Mitaku S, Demetzos C, Harvala C, Mentis A, ...
  • Pazouki N, Sankian M, Nejadsattari T, Khavari-Nejad RA, Varasteh AR. ...
  • Pazouki N, Sankian M, Leung PT, Nejadsattari T, Khavari-Nejad RA, ...
  • Pengelly A, Snow J, Mills SY, Scholey A, Wesnes K, ...
  • Rasoolijazi H, Mehdizadeh M, Soleimani M, Nikbakhte F, Farsani ME, ...
  • Sahiner UM, Birben E, Erzurum S, Sackesen C and Kalayci ...
  • Stansbury J. 2014. Rosmarinic Acid as a Novel Agent in ...
  • Swarup V, Ghosh J, Ghosh S, Saxena A, Basu A. ...
  • Ulbricht C, Abrams TR, Brigham A, Ceurvels J, Clubb J, ...
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